Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...
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The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...
"This project is a work-in-progress on HygroStructures (‘hygro’ from the root Greek word ‘hugros’, meaning ‘wet’), a new class of physical structures that conserve form, material and process.